Can I take Candesartan cilexetil and Lixiana together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no direct interaction between candesartan and Lixiana (edoxaban). However, both medications can affect your kidneys or be affected by how well your kidneys work. If your kidney function changes, it could lead to a build-up of Lixiana in your body, which increases the risk of bleeding.
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Why this happens
Candesartan is an ACE inhibitor-like drug used for blood pressure, and Lixiana is an anticoagulant (blood thinner). They do not interfere with each other's metabolism. However, candesartan can sometimes cause changes in kidney function, and Lixiana is partially cleared from the body by the kidneys.
What you should do
Back to contentsYou can safely take these two medicines together. Ensure you attend your regular blood tests to monitor your kidney function, as your doctor may need to adjust your Lixiana dose if your kidney health changes. Seek medical advice if you notice unusual bruising or bleeding.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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