Can I take Bisoprolol and Ramipril together?
Drug interaction guide
Originally published 1 Feb 2026
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Taking these two medicines together can cause your blood pressure to drop lower than usual, especially when you first start the combination or when your dose is increased. This might make you feel dizzy, lightheaded, or faint. It can also occasionally lead to increased levels of potassium in your blood or affect how your kidneys work.
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Why this happens
Both medicines work to lower blood pressure but in different ways. Bisoprolol is a beta-blocker that slows the heart rate, while ramipril is an ACE inhibitor that relaxes blood vessels. Because they both target the cardiovascular system, their effects add together (an additive effect).
What you should do
Back to contentsIt is very common for doctors to prescribe these two medicines together, especially for heart failure or after a heart attack. When you start taking them, be careful when standing up quickly from a sitting or lying position. Ensure you attend your scheduled blood tests to check your kidney function and potassium levels. If you feel severely dizzy or faint, contact your doctor.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
1 Feb 2026 | Originally published
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