Can I take Atorvastatin and Turkey tail together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no evidence of a direct harmful interaction between atorvastatin and turkey tail mushroom (Trametes versicolor). However, turkey tail may have a mild effect on how the liver processes certain medications, and it may also have its own subtle cholesterol-lowering properties.
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Why this happens
Turkey tail contains compounds called polysaccharopeptides (PSP and PSK) which primarily affect the immune system. While atorvastatin is broken down by a specific liver enzyme (CYP3A4), turkey tail does not significantly block or speed up this enzyme. There is a theoretical possibility of an 'additive effect,' meaning both substances are working to lower cholesterol at the same time.
What you should do
Back to contentsIt is generally considered safe to take these together. However, because herbal supplements are not regulated as strictly as medicines, you should inform your GP or pharmacist that you are taking turkey tail. If you experience any unusual muscle pain, tenderness, or weakness (rare side effects of statins), contact your doctor immediately.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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