Can I take Amlopadine and Aspirin together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
Taking amlodipine and aspirin together is generally considered safe, but there is a small chance that aspirin could slightly reduce how well amlodipine works to lower your blood pressure. Additionally, both medications can independently increase the risk of stomach irritation or bruising, though this is rarely a significant problem at standard doses.
In this article:
Continue reading below
Why this happens
Aspirin belongs to a group of medicines called NSAIDs. These can sometimes cause the body to hold onto salt and water, and they can interfere with natural chemicals called prostaglandins that help keep blood vessels relaxed. This can slightly counteract the blood-pressure-lowering effect of amlodipine.
What you should do
Back to contentsYou can usually take these two medicines together. However, you should monitor your blood pressure regularly to ensure it stays within the target range set by your doctor. If you notice your blood pressure rising or if you experience unusual bruising or stomach pain, speak to your GP or pharmacist.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions
Treatment and medication
Can I take Co-codamol and Ibuprofen together?
It is safe to take co-codamol and ibuprofen together. They are different types of painkillers that work in different ways to provide better pain relief than taking either one alone.
Treatment and medication
Can I take Cordyceps and Lions mane together?
There are no known negative interactions between Cordyceps and Lion's Mane mushrooms. In fact, they are frequently taken together in 'mushroom blends' because they work in different ways. Cordyceps is typically used for energy and physical stamina, while Lion's Mane is used for brain health and focus. Taking them together may provide a combined benefit for both physical and mental performance.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.
Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.