Can I take Amitriptyline and Shortec together?

Why this happens

Both medicines act on the central nervous system to slow down brain activity. Amitriptyline is a tricyclic antidepressant and Shortec is an opioid painkiller; when used together, their sedative effects add up. Additionally, both drugs have 'anticholinergic' effects, which multiply the risk of side effects like constipation and blurred vision.

You should only take these two medicines together if they have been specifically prescribed by your doctor with the knowledge that you are taking both. If you feel excessively sleepy, have shallow breathing, or feel like you might faint, seek medical help immediately. Avoid driving or operating machinery until you know how this combination affects you. Do not drink alcohol while taking these medicines.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.