Can I take Cordyceps and Shiitake together?
Drug interaction guide
Originally published 24 Jan 2026
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Both cordyceps and shiitake mushrooms have properties that can slow down blood clotting and lower blood sugar levels. Taking them together might increase the risk of bruising or bleeding, and could potentially cause your blood sugar to drop too low.
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Why this happens
These mushrooms have 'additive' effects. This means they work in similar ways: both contain compounds that can prevent platelets (blood cells) from sticking together to form clots, and both can increase insulin sensitivity or mimic insulin's effect on blood sugar.
What you should do
Back to contentsIt is generally safe for healthy individuals to consume these together in culinary amounts. However, if you are taking supplements, you should monitor for signs of easy bruising or bleeding gums. If you have diabetes or are taking blood-thinning medication (like warfarin or aspirin), consult your doctor before combining these supplements, as your dosages may need adjusting.
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Using other medicines?
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
24 Jan 2026 | Originally published
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