Can I take Magnesium and Wegovy flextouch together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known direct interaction between magnesium supplements and Wegovy (semaglutide). However, both can affect your digestive system. Wegovy slows down how quickly your stomach empties, which could theoretically change how quickly your body absorbs magnesium, though this is rarely a clinical concern. Additionally, both can cause side effects like nausea or changes in bowel habits (magnesium often softens stools, while Wegovy can cause constipation or diarrhoea).
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Why this happens
Wegovy is a GLP-1 receptor agonist that delays 'gastric emptying' (the speed at which food and pills leave the stomach). This can alter the timing of absorption for oral supplements like magnesium. There are no shared metabolic pathways or conflicting chemical actions between the two.
What you should do
Back to contentsIt is generally safe to take magnesium while using Wegovy. To ensure the best absorption and to avoid any potential stomach upset, you may wish to take your magnesium supplement at a different time of day than when you experience the most side effects from your Wegovy injection. If you experience severe diarrhoea or stomach pain, consult your doctor.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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