Can I take Danazol and Sertraline together?

Why this happens

Danazol can slow down the way your liver breaks down sertraline (by affecting enzymes like CYP3A4). This leads to higher levels of sertraline in your body. Additionally, both drugs can influence serotonin levels, which may lead to an over-accumulation of this chemical in the brain.

You should speak to your doctor before taking these two medicines together. If your doctor decides this combination is necessary, they may need to adjust your dose. Seek medical help immediately if you experience symptoms like shivering, sweating, a very high temperature, a fast heartbeat, muscle stiffness, or confusion.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.