Can I take Danazol and Naproxen together?

Why this happens

Danazol can cause the body to hold onto salt and water (fluid retention), which is a side effect also shared by NSAIDs like naproxen. Additionally, danazol may interfere with the liver enzymes (CYP enzymes) that help break down naproxen, potentially leading to higher levels of the painkiller in your system.

You can usually take these together, but you should monitor yourself for signs of fluid retention, such as swollen ankles or sudden weight gain. If you have existing heart, kidney, or liver problems, speak to your doctor before combining them. Always take naproxen with food to protect your stomach.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.