Can I take Colecalciferol and Sertraline together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There are no known significant interactions between colecalciferol (Vitamin D3) and sertraline. It is generally considered safe to take these two medications together.
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Why this happens
Colecalciferol and sertraline are processed by different pathways in the body and do not interfere with each other's absorption, metabolism, or effects.
What you should do
Back to contentsYou can continue to take both medications as prescribed by your doctor. No special precautions or monitoring are required for this specific combination.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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