Can I take Ashwagandha and Oestrogel pump-pack /actuation together?
Drug interaction guide
Originally published 25 Jan 2026
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Ashwagandha may increase the levels of oestrogen in your body, potentially making the effects of your Oestrogel stronger than intended. It might also interfere with how your body naturally balances hormones.
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Why this happens
Ashwagandha is thought to have 'pro-oestrogenic' properties, meaning it may stimulate oestrogen receptors or increase the production of precursors to oestrogen. When used with Hormone Replacement Therapy (HRT) like Oestrogel, this could lead to an additive effect, resulting in higher-than-normal oestrogen activity.
What you should do
Back to contentsYou should consult your doctor or a pharmacist before combining ashwagandha with Oestrogel. If you decide to use both, monitor yourself closely for signs of too much oestrogen, such as breast tenderness, bloating, headaches, or mood swings. Your doctor may need to monitor your hormone levels more frequently.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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